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 : Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals

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Binding: Paperback
Dewey Decimal Number: 363.17
EAN: 9780309075534
Edition: 1st
ISBN: 030907553X
Label: National Academies Press
Manufacturer: National Academies Press
Number Of Items: 1
Number Of Pages: 202
Publication Date: January 15, 2001
Publisher: National Academies Press
Studio: National Academies Press




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Editorial Review:

Product Description:
A report evaluating the National Advisory Committee's Standard Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals Report, to ensure that it complied with the 1993 report done by the NRC. Softcover.

Book Description:
Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals contains a detailed and comprehensive methodology for developing acute exposure guideline levels (AEGLs) for toxic substances from inhalation exposures.

The book provides guidance on what documents and databases to use, toxicity endpoints that need to be evaluated, dosimetry corrections from animal to human exposures, selection of appropriate uncertainty factors to address the variability between animals and humans and within the human population, selection of modifying factors to address data deficiencies, time scaling, and quantitative cancer risk assessment.

It also contains an example of a summary of a technical support document and an example of AEGL derivation. This book will be useful to persons in the derivation of levels from other exposure routes—both oral and dermal—as well as risk assessors in the government, academe, and private industry.











 






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