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Binding: HardcoverDewey Decimal Number: 616.1507 EAN: 9780415420099 Edition: 1 ISBN: 0415420091 Label: Informa Healthcare Manufacturer: Informa Healthcare Number Of Items: 1 Number Of Pages: 319 Publication Date: January 28, 2008 Publisher: Informa Healthcare Studio: Informa Healthcare Related Items:
Editorial Review: Product Description: Cytogenetics, fluorescence in situ hybridization (FISH) and molecular tests, especially polymerase chain reaction (PCR), play an important role in the management of patients with hematologic malignancies by helping to establish the diagnosis, as well as predict prognosis, response to treatment and disease progression. Chromosomal and molecular abnormalities provide the most reliable criteria for classification of hematopoietic tumors and often comprise the basis for targeted therapy. Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies, provides a review of chromosomal and molecular changes in hematologic malignancies and correlates the karyotypic and genetic abnormalities with morphology, immunophenotype and clinical data. With over 180 figures and diagnostic algorithms, this text is essential reading for all pathologists, hematopathologists, hematologic oncologists, cytogenetists, cytogenetic technologists and cell biologists. Average Rating:
 Rating:  - Too many errorsThe plethora of errors (typographical, grammatical, technical) raises the possibility that no serious editing/proofreading was performed on this edition. In addition, many tables were printed too small to read without the assistance of a magnifying glass. The technical quality of the karyotypes was surprisingly suboptimal. While I was using this text as a review for an upcoming board exam, I had the advantage of knowing the identity of pertinent breakpoint identifications and could recognize incorrect ... Read More Rating:  - Brave new (molecular) worldAs a PhD graduate, beginning my Clinical Molecular Genetics fellowship, I highly recommend this new text as a review of the known cytogenetic and molecular abnormalities, causing hematological malignancies. This is a continuation of the great series of books from Dr. Gorczyca, who realizes that there is a shift in hematopathology away from plain morphology and special stains (covered in his Atlas of Differential Diagnosis in Neoplastic Hematopathology) to flow cytometry (as covered in his Flow Cytometry ... Read More 
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