Books for Prep | |
 Availability: Available for download now
Format: HTML Label: Wayne State University Press Manufacturer: Wayne State University Press Number Of Pages: 18 Publication Date: October 01, 1994 Publisher: Wayne State University Press Release Date: July 28, 2005 Studio: Wayne State University Press Browse for similar items by category: Click to Display Editorial Review: Product Description: This digital document is an article from Human Biology, published by Wayne State University Press on October 1, 1994. The length of the article is 5163 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. From the author: The genetic structure of the Utah Mormon population is examined using 25 blood group and 47 RFLP alleles obtained from 442 subjects living in 8 geographic subdivisions. Nei's [G.sub.ST] was 0.013 (p [is less than] 0.002) for the RFLP data and 0.012 (p [is greater than] 0.4) for the blood group data, showing that only 1% of the genetic variance in this population can be attributed to subdivision effects. A comparison of intersubdivision distance matrices based on blood groups, RFLPs, migration matrices, isonymy, and pedigrees shows that genetic distances have relatively low and nonsignificant correlations with the other three types of data. However, the correlations based on RFLPs are considerably higher than those based on blood groups. Relationship matrices based on interindividual allele sharing were compared with known genealogical kinship coefficients between each pair of individuals. The correlation between the blood group and RFLP relationship matrices was small but marginally significant using the Mantel test (r = 0.014, p [is less than] 0.06). The RFLP relationship matrix correlated more highly with genealogical kinship than did the blood group relationship matrix (r = 0.023, p [is less than] 0.0001 and r = 0.012, p [is less than] 0.001, respectively). These correlations increased by approximately one order of magnitude when pairs of subjects having zero kinship coefficients were excluded. These results show that genetic distances derived from RFLPs correlate more strongly with other types of kinship than do distances based on blood groups. This probably reflects the fact that RFLPs are more neutral, have frequencies that are more accurately estimated, and contain more information about DNA sequence variation. Citation Details Title: Genetic structure of the Utah Mormons: comparison of results based on RFLPs, blood groups, migration matrices, isonymy, and pedigrees. (restriction fragment length polymorphisms) Author: Elizabeth O'Brien Publication: Human Biology (Refereed) Date: October 1, 1994 Publisher: Wayne State University Press Volume: v66 Issue: n5 Page: p743(17) Distributed by Thomson Gale 
In association with Amazon.com | |